Key pathologies
L’Hépatite
Hepatitis
- Pathogens: HBV and HCV (the primary causes of chronic hepatitis)
Public health issues:
- HBV and HCV responsible for more than 1 million deaths per year
- Hepatitis: 5-10% of liver transplants
Respiratory diseases
Diseases
- tuberculosis, influenza, pneumonia, RSV infection and legionellosis
- Priority on tuberculosis
Public health issues associated with tuberculosis:
- 8-10 million new cases per year
- 2-3 million deaths per year
- 2 billion individuals infected by Mycobacterium (high risk of reactivation and transmission of virus)
- Strong synergy with HIV
- Dramatic increase in multidrug resistance (MDR and XDR).
Nosocomial diseases
Pathogens
- E. coli , S. Aureus, P. aeruginosa, Enterococcus spp., coagulase-negative staphylococci, Candida spp., Klebsiella spp., Enterobacter spp, Clostridium difficile
- Priority on S. Aureus
Public health issues (estimated figures from ECDC):
- Risk of contracting an infection in hospital: 7%
- 4,450,000 individuals infected per year
- 40,000 deaths per year
